Communication

Dalton Trans., 2008, 6364 - 6367, DOI: 10.1039/b815404j

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Altering pyridinone N-substituents to optimise activity as potential prodrugs for Alzheimer's disease

Lauren E. Scott, Brent D. G. Page, Brian O. Patrick and Chris Orvig

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Selective design modifications of specifically substituted 3-hydroxy-4(1H)-pyridinones show possibly advantageous ring freedom while maintaining metal-binding ability and antioxidant capacity, moving toward an efficient potential treatment for Alzheimer's disease.

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