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Biology in Focus


26 June 2007

 Biology in Focus graphic

Biology in Focus highlights and draws together research in key areas at the chemistry/biology interface. Each quarterly instalment showcases a different subject area, providing scientists with an opportunity to browse and view related science on specific themes. Research material is primarily drawn from three RSC journals: Molecular BioSystemsLab on a Chip and The Analyst

The second theme is 'Microarrays'. 


Theme 2: Microarrays


Protein, DNA, cell and even tissue microarrays offer fantastic opportunities for high throughput analysis of biological and biochemical events.  New methods of fabrication, analysis and applications of microarrays all contribute to this fast moving area of research.

Forum Articles

Surface free energy and microarray deposition technology
Glen McHale, Analyst, 2007, 132, 192
DOI: 10.1039/b617339j


Highlights

Transcriptomic signatures in breast cancer
Jianjiang Fu and Stefanie S. Jeffrey, Mol. BioSyst., 2007, 3, 466
DOI: 10.1039/b618163e


Heightened sense for sensing: recent advances in pathogen immunoassay sensing platforms
Nicholas O. Fischer, Theodore M. Tarasow and Jeffrey B.-H. Tok, Analyst, 2007, 132, 187
DOI: 10.1039/b615477h


Fish n chips: the use of microarrays for aquatic toxicology
Nancy D. Denslow, Natālia Garcia-Reyero and David S. Barber, Mol. BioSyst., 2007, 3, 172
DOI: 10.1039/b612802p


Papers

Bi-functionalization of a patterned Prussian blue array for amperometric measurement of glucose via two integrated detection schemes
Na Zhang, Thomas Wilkop, Soohyun Lee and Quan Cheng, Analyst, 2007, 132, 164
DOI: 10.1039/b611357e


A novel antibody microarray format using non-covalent antibody immobilization with chemiluminescent detection
Kazue Usui-Aoki, Kiyo Shimada and Hisashi Koga, Mol. BioSyst., 2007, 3, 36
DOI: 10.1039/b612492e


Single-cell electroporation arrays with real-time monitoring and feedback control
Michelle Khine, Cristian Ionescu-Zanetti, Andrew Blatz, Lee-Ping Wang and Luke P. Lee, Lab Chip, 2007, 7, 457
DOI: 10.1039/b614356c


Fluorescent microsphere fiber optic microsensor array for direct iodide detection at low picomolar concentrations
Katarzyna Wygladacz and Eric Bakker, Analyst, 2007, 132, 268
DOI: 10.1039/b614562k


Active 3-D microscaffold system with fluid perfusion for culturing in vitro neuronal networks
Laura Rowe, Mahmoud Almasri, Kil Lee, Nick Fogleman, Gregory J. Brewer, Yoonkey Nam, Bruce C. Wheeler, Jelena Vukasinovic, Ari Glezer and A. Bruno Frazier, Lab Chip, 2007, 7, 475
DOI: 10.1039/b700795g


A microfluidic device based on droplet storage for screening solubility diagrams
Philippe Laval, Nicolas Lisai, Jean-Baptiste Salmon and Mathieu Joanicot, Lab Chip, 2007, 7, 829
DOI: 10.1039/b700799j


Technical Notes

A plate reader-compatible microchannel array for cell biology assays
Hongmei Yu, Caroline M. Alexander and David J. Beebe, Lab Chip, 2007, 7, 388
DOI: 10.1039/b612358a


Microfluidic fabrication of addressable tethered lipid bilayer arrays and optimization using SPR with silane-derivatized nanoglassy substrates
Joseph D. Taylor, K. Scott Phillips and Quan Cheng, Lab Chip, 2007, 7, 927
DOI: 10.1039/b618940g


Methods

A novel SNP detection technique utilizing a multiple primer extension (MPEX) on a phospholipid polymer-coated surface
Kazuhide Imai, Yasukazu Ogai, Daisuke Nishizawa, Shinya Kasai, Kazutaka Ikeda and Hisashi Koga, Mol. BioSyst., 2007, 3, 547
DOI: 10.1039/b701645j


Previous Themes

Theme 1: Cancer and other disease states

Research at the biology/chemistry interface